|
|
KySat Conference
The second annual KySat Conference was held May 7 in Lexington, KY. Go to www.kysat.com for details.
AdvanceKentucky
April 2, 2008. Today KSTC announced the first 12 Kentucky high schools to participate in the National Math and Science Initiative. Click here for details.
AdvanceKentucky Employment Opportunities
|
|
|
Search Portfolio Projects and Investments
County Impact Map
959 Entries Found
|
Organization / Applicant |
Project Description |
Focus Area |
Award |
Fund |
NaugaNeedles, LLC
Yazdanpanah Mehdi
County |
Nanoneedle Array for High Resolution Electrical Impedance Nanotomographic Imaging of Biofilms
|
Biosciences
|
$2,000
|
SBIR/STTR Phase 0 |
Pharmacogenetics Diagnostic Laboratory, LLC
Diana Maslowski
County |
Development of a Personalized Medicine Interface for the Safe and Effective Treatment of Patients Undergoing Warfarin Therapy
|
Biosciences
|
$3,100
|
SBIR/STTR Phase 0 |
ChemPharma Intl., LLC
Rodney Eisenberg
County |
Synthesis of Labeled Reference Standards for Horse Racing Forensic Toxicology Worldwide
|
Biosciences
|
$4,000
|
SBIR/STTR Phase 0 |
University of Kentucky
David Hildebrand
Fayette County |
Commercialization of green note production technology
The purpose of this project is to conduct pilot scale production of green note molecules using the lab-scale proprietary production technology we developed. From this we will determine the cost of production and quality (purity) of products from scaled-up production as a way forward for commercialization of this technology.
|
Biosciences
|
$74,031
|
KSEF |
University of Louisville
Lee Dugatkin
Jefferson County |
The evolution of intelligence in a model invertebrade system
Ruling out or confirmation of complex learning in an Octopus bimaculoides could change the way scientists think about the evolution of cognition, and might also affect the placement of complex learning within the hierarchy of intellectual skills measured in animals.
|
Biosciences
|
$19,385
|
KSEF |
University of Kentucky
Lynne Rieske-Kinney
Fayette County |
innovative approach for elucidating trophic relationships of an invasive forest pest
This project utilizes an innovative approach to mitigate the effects of an exotic, invasive insect, the hemlock woolly adelgid (Adelges tsugae), threatening a foundation forest tree species, the eastern hemlock (Tsuga canadensis). Using an adelgid-specific monoclonal antibody recently developed by the PI's, this project will use immunological techniques to understand the role of natural enemies in regulating populations of the adelgid.
|
Biosciences
|
$19,997
|
KSEF |
University of Kentucky
Luke Bradley
Fayette County |
Neuronal protein recognition, specificity, and design
This project will use protein design and molecular screening approaches to generate new molecules to increase our understanding of neuroprotein structure and function. Work from this project will establish a foundation for further downstream bioapplications.
|
Biosciences
|
$20,000
|
KSEF |
University of Kentucky
Michael Murphy
Fayette County |
Development of an Assay System for the Measurement of ß-Secretase
â-secretase is the main enzyme critical for the development of Alzheimer’s disease. However, existing ways to measure this enzyme are inadequate. This proposal is focused on the development of a better assay.
|
Biosciences
|
$20,000
|
KSEF |
University of Kentucky
Arthur Hunt
Fayette County |
Uncoupling the timing of flowering from stress in plants
Exploring possible linkages between calmodulin signaling and flowering in plants. These studies will address the hypothesis that calmdoulin signaling impacts the timing of flowering through an interaction with an RNA processing factor, and will lead to further insight into the means by which stimuli that act through calcium and calmodulin may affect flowering in plants
|
Biosciences
|
$19,970
|
KSEF |
University of Louisville
Janina Ratajczak
Jefferson County |
Hematopoietic differentiation of VSEL stem cells
We will test the hypothesis that very small embryonic like stem cells (VSELs) isolated from adult bone marrow could be the most primitive pluripotent stem cells in BM that are able to differentiate along the hematopoietic lineage i) we will evaluate by employing in vitro assays the differentiation of these into different hematopoietic lineages and ii) we will also study if these cells may contribute to long term hematopoiesis after transplantation into lethally irradiated syngeneic littermates.
|
Biosciences
|
$20,000
|
KSEF |
University of Kentucky
Jian Sheng
Fayette County |
Development of Micro-actuated Artificial Mucus Layer for Drag Management and Flow Control for Unmanned Micro Vehicles
The project is to develop a micro-scale artificial mucus layer that is actively actuated by an array of micro-actuators fabricated from smart materials to generate a traveling wave within the layer such that mass and momentum transfers are enhanced and consequently wall shear stress can be managed. In the project, a proof-of-concept mucus layer and its manufacturing techniques, actuation schemes will be developed, and its preliminary performance will be evaluated as well.
|
Biosciences
|
$20,000
|
KSEF |
University of Kentucky
Gregory Frolenkov
Fayette County |
Imaging of surface nanostructures in a living cell
This project will develop first non-contact nanoscale-resolution technique for imaging surface of the cell in the physiological environment. This technique will be useful in the study of a number of human diseases that impact events at the plasma membrane of the cell.
|
Biosciences
|
$20,000
|
KSEF |
University of Kentucky
Eric Grulke
Fayette County |
Scale-up of DNA encapsulation processes
This project will develop proof-of-concept for using process mixing technology to produce particles of DNA encapsulated in polymers suitable for gene therapy and other applications. This engineering information would form the basis of an NIH STTR submission by Coldstream Labs, Inc.
|
Biosciences
|
$19,999
|
KSEF |
University of Kentucky
Robert Houtz
Fayette County |
Isolation and Identification of Plant-Specific Peptide Deformylase Inhibitors from Soil
Microorganisms for Use as Broad-Spectrum Herbicides and Selectable Markers.
Novel genetically engineered cell lines will be created and used as high-throughput screening tools to identify natural products with activity as inhibitors against plant peptide deformylase. Inhibitors of plant peptide deformylase have significant potential as alternative broad-spectrum herbicides that do not rely on genetically engineered foreign genes for crop resistance, and are valuable as selectable marker tools in plant transformation vectors.
|
Biosciences
|
$19,976
|
KSEF |
Northern Kentucky University
Richard Durtsche
campbell County |
Development of technologies for the detection of trigger mechanisms of gastric activities using tadpoles as a model of vertebrate digestion
This project, will with undergraduate research students develop and test a chamber (modified Ussing chamber) that will allow for continual perfusion of the frog tadpole stomach lining with food or drug solutions for the measurement, with our lab fabricated pH micro-probes, of acid production by cells of the stomach lining. We will test these technologies to measure pH (acid) changes on varying developmental stages of frog tadpoles stomachs using the human proton (H+ ion) pump inhibitor esomeprazole (e.g., Nexium®) to investigate the developmental role of gastric activity in vertebrates.
|
Biosciences
|
$19,417
|
KSEF |
University of Kentucky
David Hildebrand
Fayette County |
Cyclopropane fatty acid production in plants
The goal of this project is to develop renewable, environmentally friendly motor oils that can meet today’s high performance automobile and other engine specifications. This will be achieved by transferring the natural ability of some plants to make oils of such properties to oilseed crops that can be economically produced in Kentucky.
|
Biosciences
|
$19,853
|
KSEF |
University of Kentucky
Robert Lodder
Fayette County |
Device for Prevention of Heart Attack and Stroke
Development of an innovative method of serum analysis using multidimensional spectroscopy to improve the cost effectiveness of lipoprotein screening for the prevention of heart attack and stroke.
|
Biosciences
|
$60,000
|
KSEF |
University of Kentucky
Karen Novak
Fayette County |
Efficacy of Synthetic Antimicrobial Peptides Against Oral Biofilms
The effectiveness of treating oral infections, such as dental caries, periodontal disease and other oral biofilm-associated diseases with a topical application of a new group of synthetic antimicrobial peptides.
|
Biosciences
|
$15,000
|
KSEF |
University of Kentucky
Fred Payne
Fayette County |
Sensor Technology Development for Monitoring and Control of Curd Syneresis
Development of technology to control a critical step in cheese processing which affects cheese moisture, specifically the step of choosing when to separate the curd from the whey.
|
Biosciences
|
$15,000
|
KSEF |
University of Kentucky
Pradeep Kachroo
Fayette County |
Identifications of signal(s) modulating cross talk between defense signaling pathways
Identification of the biochemical basis of specific defense responses (cross talk in activated signaling pathways) between plants and a given pathogen.
|
Biosciences
|
$14,850
|
KSEF |
Tribo Flow Separations
John Stencel
Fayette County |
Instrumentation for the Control of Foam Fractionation Columns
A new instrument concept is developed that automates operation of foam fractionation columns for extracting and enriching valuable biological molecules from plants. Characteristic properties of and processes within fractionation columns are measured, correlations are established with the corresponding extraction efficiencies of specific biological molecules, and then a prototype instrument designed for pharmaceutical protein production facilities.
|
Biosciences
|
$47,108
|
KSEF |
University of Kentucky
Czarena Crofcheck
Fayette County |
Utilization of Nickel Nanoparticles to Facilitate the Recovery of Histidine Tagged Proteins
Transgenic tobacco can be used as a solar powered bioreactor to produce commercially attractive pharmaceuticals or enzymes. This project will investigate the feasibility of using a novel separation technique to recover proteins from tobacco extract using nickel nanoparticles, histidine-tagged proteins, and a magnetic field.
|
Biosciences
|
$15,000
|
KSEF |
ECM Biosciences
Mark Wilson
Woodford County |
Development of Antibody-based Technologies for Axon Regeneration after Spinal Cord injury
ECM Biosciences will develop antibody-based technologies that target inhibitory molecul | | | |
